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The Postgenomic Era, or Why We Need 300,000 Mice Strains

There is no need to prove that the question on how a living organism functions is topical for each of us. The only problem is to choose an adequate “tool” for knowledge acquisition. As a rule, research into any biological system be it a cell, individual, or biocenosis commences from a “morphological” structural description. However, though this stage is necessary, it alone is insufficient for comprehending the functioning mechanisms of a studied system. A brilliant illustration of how extremely erroneous...

Modified: 30.08.2008
genotype , genetically engineered mice , transgenic mice , knockout genes , knockout mice , gene expression , GFP , point mutations , genetic lines , embryo , cryobank , cryoarchive , SPF-animals , SPF-vivarium , Institute of Cytology and Genetics SB RAS
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Parasitosis from A to T

Perhaps, the large-scale project aimed at a complete genomicsand proteomics-based decoding of Opisthorchis felineus, launched at the Institute of Cytology and Genetics, Siberian Branch of the Russian Academy of Sciences, will not only implement its minimum program—to understand the nature of the parasitosis caused by this agent and reliably control it but also fill the almost complete vacuum in the genomic research in Russia Historically, studies in the field of experimental biology have followed...

Modified: 30.04.2008
opisthorchiasis , liver fluke , opisthorchis , helminthosis , genome project , genome sequencing , genome research , diagnostics , diagnostic test systems , genomics , proteomics , bioinformatics , Institute of Cytology and Genetics SB RAS
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