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The Postgenomic Era, or Why We Need 300,000 Mice Strains

..., D. Whittingham, a British scientist, and his colleagues (in 1972, this particular team discovered the method for freezing embryos) continue today to produce mice using the embryos that they “canned” over 30 years ago: the embryos stored in the cryobank did not at all lose their ability “to revive.” The story of how the first in the world (and still the largest one) cryobank of mouse genotypes with the Jackson Laboratory (USA) was set up is quite didactic. Its construction was initiated ...

Modified: 30.08.2008
genotype , genetically engineered mice , transgenic mice , knockout genes , knockout mice , gene expression , GFP , point mutations , genetic lines , embryo , cryobank , cryoarchive , SPF-animals , SPF-vivarium , Institute of Cytology and Genetics SB RAS
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The Postgenomic Era. Cryoarchiving by the Example of Mustelids

... families is not much better than with Felidae. The list of endangered Mustelidae species is also quite impressive (Schreiber et al. 1989). As the methods traditionally used for in situ or ex situ preservation of mammalian species are expensive, cryobanking became popular as an approach for these species preservation (Amstislavsky et al., 2008). Another reason for the popularity of reproductive biotechnology is the rapid increase of the overall number of transgenic and knockout mouse strains,...

Modified: 30.08.2008
mustelids , ferrets , stoats , carnivores , reproductive technologies , cryobank , embryo freezing , embryo , cryopreservation , transplantation
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