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Biochips: Diagnosis Is a Matter of Technique!

... vital activities of our cells are regulated. An intricate network of molecular interactions controls the processes of intracellular metabolism, cell division, and differentiation; this network determines the level of expression (functioning) of various genes. The concentration of the corresponding messenger RNA (mRNA), which is synthesized on the template of DNA, the carrier of hereditary information, reflects the expression level. The dynamics of changes in the concentration of a certain mRNA indicate ...

Modified: 25.10.2007
biochips , microchips , DNA , RNA , nucleic acids , genes , gene expression , diagnosis
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The Remedy for Genes

Physicians have always dreamed of substances that would act on particular genes, i. e., on the root of many diseases. Indeed, such substances make it possible to create drugs, actual “magic bullets”, capable of influencing the hereditary material of various infectious agents without any harm to the human body and ...

Modified: 25.04.2007
nucleic acids , oligonucleotides , RNA , chemical modification , genes
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Jumping GENES

In the middle of the last century, Barbara McClintock, an American researcher, discovered amazing genes in corn that were able, on their own, to change their position on chromosomes. Today they are called “jumping genes”, or “transposable (mobile) elements”. This discovery was not recognized for a long time or was regarded ...

Modified: 25.02.2007
mobile elements , Drosophila melanogaster , genome , genes , DNA
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The Planet's Long Youth

... (Chetverin and Chetverina, 1993) or to reproduce in the appropriate conditions, like bacteria, was studied in experiments at the Institute of Protein (Moscow). Remaining in contact with the ambient medium, RNA colonies become easily involved in transgenesis, which is possible even through air. RNA colonies upon montmorillonite, with a water film on the surface, may have been the earliest non-cellular systems that turned to evolution. Molecules in those systems could have been in charge of different ...

Modified: 30.05.2005
Zavarzin , bacteria , RNA , Earth , biomass , eukaryotes , evolution , evolution of life , genes
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Nucleotide Chronicles of Troubled Time

... distinct from other species. The efforts to define ‘biological species’ yielded ‘coalescent’ definitions considering ‘a species’ as a group of individuals whose uniformity is maintained by special mechanisms. Not By A Net Alone … How are genes compared? The principle of comparative analysis of DNA is simple. It suggests that the same functions are fulfilled, as a rule, by homologous , i. e., similar, proteins. For example, hemoglobins, blood proteins, are in everybody, in humans, animals,...

Modified: 30.05.2004
Lake Baikal , speciation , genes , genome , evolution , DNA , biodiversity
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