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Phosphoryl Guanidines: New Chemical Analogues of Nucleic Acids

Researchers from the Institute of Chemical Biology and Fundamental Medicine, Siberian Branch, Russian Academy of Sciences (ICBFM SB RAS; Novosibirsk, Russia) have discovered a new class of nucleic acid analogues that have a potential for developing into efficient gene-targeting therapeutics ‘Ex Siberia semper novi’ is how Ivan Efremov, an outstanding Russian writer, scientist and thinker of the Soviet epoch, reworded in his novel The Razor’s Edge the almost forgotten phrase of Pliny the Elder...

Modified: 30.08.2015
DNA , oligonucleotide analogs , phosphoryl guanidine
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