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Phosphoryl Guanidines: New Chemical Analogues of Nucleic Acids

... treating diseases by using derivatives of nucleic acids. Today, the legacy of Grineva and Knorre has enabled their modern successors to get their bit of luck. Recently, Novosibirsk chemists have synthesized a new class of nucleic acid analogues, namely, phosphoryl guanidines (Kupryushkin, Pyshnyi, and Stetsenko, 2014). When an unloaded rifle fires a shot What is similar and what is different between common nucleic acids and phosphoryl guanidines? A natural DNA or RNA molecule contains negatively charged ...

Modified: 30.08.2015
DNA , oligonucleotide analogs , phosphoryl guanidine
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